W.H.'s Update 9th - 17 th June
9th June
Drying of EPC 6 and 10
10th June
1) Synthesis of EPC A & B (Drying)
EPC A: 2 g PEG, 1 g PPG, 0.05 g PCL
EPC B: 2 g PEG, 1 g PPG, 0.10 g PCL
2) Reaction of EPC 6 & 10
11th June
1) Re-synthesis of EPC 8
Reason: previous polymer has too low molecular mass. Not suitable for drug delivery use.
2) Reaction of EPC A and B
12 th June
1) Precipitation of EPC 6 and 10
2) Reaction of EPC
3) Earlier Precipitation of EPC A 8
Reason: Polymer formed has a thick mixture. Further reaction may result in cross-linking of the polymer.
4) Synthesis of 2nd batch of EPC 7 (Drying)
13th June
1) Extraction of EPC 6, 10, and A --- Decanting the ether and blow drying the polymer, followed by dissolving in chloroform and leaving in the fumehood to evaporate.
2) Reaction of 2nd batch of EPC 7
17th June
1) Precipitation of 2nd batch of EPC 7.
Drying of EPC 6 and 10
10th June
1) Synthesis of EPC A & B (Drying)
EPC A: 2 g PEG, 1 g PPG, 0.05 g PCL
EPC B: 2 g PEG, 1 g PPG, 0.10 g PCL
2) Reaction of EPC 6 & 10
11th June
1) Re-synthesis of EPC 8
Reason: previous polymer has too low molecular mass. Not suitable for drug delivery use.
2) Reaction of EPC A and B
12 th June
1) Precipitation of EPC 6 and 10
2) Reaction of EPC
3) Earlier Precipitation of EPC A 8
Reason: Polymer formed has a thick mixture. Further reaction may result in cross-linking of the polymer.
4) Synthesis of 2nd batch of EPC 7 (Drying)
13th June
1) Extraction of EPC 6, 10, and A --- Decanting the ether and blow drying the polymer, followed by dissolving in chloroform and leaving in the fumehood to evaporate.
2) Reaction of 2nd batch of EPC 7
17th June
1) Precipitation of 2nd batch of EPC 7.
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