Friday, June 27, 2008

W.H.'s Update 9th - 17 th June

9th June

Drying of EPC 6 and 10


10th June

1) Synthesis of EPC A & B (Drying)

EPC A: 2 g PEG, 1 g PPG, 0.05 g PCL
EPC B: 2 g PEG, 1 g PPG, 0.10 g PCL


2) Reaction of EPC 6 & 10


11th June

1) Re-synthesis of EPC 8

Reason: previous polymer has too low molecular mass. Not suitable for drug delivery use.

2) Reaction of EPC A and B


12 th June

1) Precipitation of EPC 6 and 10

2) Reaction of EPC

3) Earlier Precipitation of EPC A 8

Reason: Polymer formed has a thick mixture. Further reaction may result in cross-linking of the polymer.

4) Synthesis of 2nd batch of EPC 7 (Drying)


13th June

1) Extraction of EPC 6, 10, and A --- Decanting the ether and blow drying the polymer, followed by dissolving in chloroform and leaving in the fumehood to evaporate.

2) Reaction of 2nd batch of EPC 7


17th June

1) Precipitation of 2nd batch of EPC 7.


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