Ed's Update

Completed target:

- All CMCs on new EPCs including recently made new EPC 6

To be completed:

- Drug delivery on EPC 6 made on 6th June




Future Plans:

- New Drug Delivery sequence to be repeated with improved methods to lessen the chances of disrupting the drug delivery due to human errors.

During this run of Drug Delivery, various human error surfaced includes,

1) Mishandling of the vials, causing the vial to topple and agitate all the polymer that has being eroded away.

2) Capping and opening vials is a risky process and requires careful attention cause it might slip or spill if we apply too much force.

3) The position of the vials have to be secured in the waterbath because incidents of the vials floating or topple in the bath is a frequent problem.


To solve these problems:

1) Floats should be used and vials attached to the float to allowed the vials to float in the waterbath. Most probably 3 vials per float. By doing so, the handling process is much easiler as u can grab the float altogether which is 1 EPC sample with 3 replications.

2) I suggest not to open and close the cap anymore, all drug delivery process uses a needle and a syringe. This completely eliminates the problem of spillage and slips. There might be a problem at piercing into the cap too much creates a hole which allows water vapour to go in, so we might be able to use a tape after every piercing to cover the hole.

3) Positions of the vials are solved with the use of floats as it will not topple floating on the surface of water. There is also a suggestion to make a Styrofoam platform manually by ourself to hold the samples when we take them out so that it will be steady on the table while we extract the sample we need.



These changes will be tested for their reliably to be used for the next drug delivery run.